Ren-Yuan Bai Selected Research

Mebendazole (Anti-Worm)

1/2021	Mebendazole and temozolomide in patients with newly diagnosed high-grade gliomas: results of a phase 1 clinical trial.
1/2020	Preventative Effect of Mebendazole against Malignancies in Neurofibromatosis 1.
10/2016	Mebendazole and a non-steroidal anti-inflammatory combine to reduce tumor initiation in a colon cancer preclinical model.
8/2015	Brain Penetration and Efficacy of Different Mebendazole Polymorphs in a Mouse Brain Tumor Model.
4/2015	Effective treatment of diverse medulloblastoma models with mebendazole and its impact on tumor angiogenesis.
1/2015	Repurposing the antihelmintic mebendazole as a hedgehog inhibitor.
9/2011	Antiparasitic mebendazole shows survival benefit in 2 preclinical models of glioblastoma multiforme.

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Ren-Yuan Bai Research Topics

Disease

14	Neoplasms (Cancer) 01/2022 - 01/2015
5	Brain Neoplasms (Brain Tumor) 01/2022 - 09/2011
5	Medulloblastoma 01/2021 - 11/2012
5	Glioblastoma (Glioblastoma Multiforme) 01/2021 - 06/2011
3	Glioma (Gliomas) 01/2021 - 09/2011
2	Neurofibrosarcoma (MPNST) 01/2020 - 01/2019
2	Neurofibromatosis 1 (Neurofibromatosis Type I) 01/2020 - 01/2019
2	Cytokine Release Syndrome 01/2020 - 12/2018
2	Genetic Translocation (Chromosomal Translocation) 02/2004 - 08/2003
2	Lymphoma (Lymphomas) 02/2004 - 08/2003
1	COVID-19 01/2020
1	Infections 12/2018
1	Sarcoma (Soft Tissue Sarcoma) 01/2017
1	Adenomatous Polyposis Coli (Familial Adenomatous Polyposis) 10/2016
1	Adenoma (Adenomas) 10/2016
1	Colonic Neoplasms (Colon Cancer) 10/2016
1	Polyps 10/2016
1	Edema (Dropsy) 03/2015
1	Hypoxia (Hypoxemia) 03/2015
1	Echinococcosis (Hydatid Cysts) 01/2015
1	Enterobiasis 09/2011
1	Parasitic Diseases (Parasitic Disease) 09/2011
1	Anaplastic Large-Cell Lymphoma (Ki 1 Lymphoma) 02/2004

Drug/Important Bio-Agent (IBA)

7	Mebendazole (Anti-Worm)FDA Link 01/2021 - 09/2011
2	Pharmaceutical PreparationsIBA 01/2021 - 06/2011
2	Antiparasitic Agents (Antiparasitics)IBA 08/2015 - 09/2011
2	Anaplastic Lymphoma KinaseIBA 02/2004 - 08/2003
1	Hydroxyurea (Hydrea)FDA LinkGeneric 01/2022
1	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA 01/2021
1	Cisplatin (Platino)FDA LinkGeneric 01/2021
1	Oncogene Proteins (Oncogene Protein)IBA 01/2021
1	AnthelminticsIBA 01/2021
1	Transcription Factors (Transcription Factor)IBA 01/2021
1	Temozolomide (Temodar)FDA LinkGeneric 01/2021
1	Guanosine Triphosphate (GTP)IBA 01/2020
1	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 01/2020
1	Adrenergic Antagonists (Antiadrenergic Agents)IBA 01/2020
1	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 01/2020
1	ras ProteinsIBA 01/2019
1	Neurofibromin 1 (Neurofibromin)IBA 01/2019
1	alpha-Methyltyrosine (Metirosine)FDA Link 12/2018
1	CatecholaminesIBA 12/2018
1	AntibodiesIBA 12/2018
1	Doxorubicin (Adriamycin)FDA LinkGeneric 04/2017
1	GelatinIBA 04/2017
1	Drug CombinationsIBA 10/2016
1	Sulindac (Copal)FDA LinkGeneric 10/2016
1	Investigational DrugsIBA 08/2016
1	TabletsIBA 08/2015
1	ElacridarIBA 08/2015
1	HhAntag691IBA 04/2015
1	Phosphotransferases (Kinase)IBA 04/2015
1	Vascular Endothelial Growth Factor Receptor-2 (Vascular Endothelial Growth Factor Receptor 2)IBA 04/2015
1	Anti-Bacterial Agents (Antibiotics)IBA 03/2015
1	Antineoplastic Agents (Antineoplastics)IBA 01/2015
1	podocalyxinIBA 01/2013
1	Proteins (Proteins, Gene)FDA Link 01/2013
1	Otx Transcription FactorsIBA 11/2012
1	benzimidazoleIBA 09/2011
1	FenbendazoleIBA 09/2011
1	Pyridinolcarbamate (P23)IBA 02/2004
1	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 08/2003

Therapy/Procedure

9	Therapeutics 01/2022 - 06/2011
2	Immunotherapy 12/2018 - 08/2016
2	Drug Therapy (Chemotherapy) 01/2017 - 08/2016